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1

Unidirectional migration of osteosarcoma cells with osteoblast characteristics in response to products of bone resorption

Gregory R. Mundy, Sevgi B. Rodan, Robert J. Majeska, Sandra DeMartino, Carol Trimmier, T. John Martin, Gideon A. Rodan

Journal:

Calcified Tissue International

Year:

1982

Language:

english

File:

PDF, 402 KB

english, 1982

2

Retinoic acid effects on an SV-40 large T antigen immortalized adult rat bone cell line

Marie-Helene Lafage-Proust, Gregg Wesolowski, Matthias Ernst, Gideon A. Rodan, Sevgi B. Rodan

Journal:

Journal of Cellular Physiology

Year:

1999

Language:

english

File:

PDF, 237 KB

english, 1999

3

ChemInform Abstract: Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L.

Jean-Pierre Falgueyret, Renata M. Oballa, Osamu Okamoto, Gregg Wesolowski, Yves Aubin, Robert M. Rydzewski, Peppi Prasit, Denis Riendeau, Sevgi B. Rodan, M. David Percival

Journal:

Year:

2001

File:

PDF, 28 KB

2001

4

Rational Design of Potent and Selective NH-Linked Aryl/Heteroaryl Cathepsin K Inhibitors.

Joel Robichaud, Christopher Bayly, Renata Oballa, Peppi Prasit, Christophe Mellon, Jean-Pierre Falgueyret, M. David Percival, Gregg Wesolowki, Sevgi B. Rodan

Journal:

Year:

2004

File:

PDF, 10 KB

2004

5

Nonpeptide αvβ3 Antagonists: Identification of Potent, Chain-Shortened 7-Oxo RGD Mimetics.

Amy E. Zartman, Le T. Duong, Carmen Fernandez-Metzler, George D. Hartman, Chih-Tai Leu, Thomayant Prueksaritanont, Gideon A. Rodan, Sevgi B. Rodan, Mark E. Duggan, Robert S. Meissner

Journal:

Year:

2005

File:

PDF, 20 KB

2005

6

Erratum to “An activity-based probe for the determination of cysteine cathepsin protease activities in whole cells” [Anal. Biochem. 335 (2004) 218–227]

Jean-Pierre Falgueyret, W. Cameron Black, Wanda Cromlish, Sylvie Desmarais, Sonia Lamontagne, Christophe Mellon, Denis Riendeau, Sevgi B. Rodan, Paul Tawa, Gregg Wesolowski, Kathryn E. Bass, Shankar V

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 66 KB

english, 2005

7

Rational design of potent and selective NH-linked aryl/heteroaryl cathepsin K inhibitors

Joël Robichaud, Christopher Bayly, Renata Oballa, Peppi Prasit, Christophe Mellon, Jean-Pierre Falgueyret, M David Percival, Gregg Wesolowski, Sevgi B Rodan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 356 KB

english, 2004

8

Nonpeptide αvβ3 antagonists. Part 9: Improved pharmacokinetic profile through the use of an aliphatic, des-amide backbone

David B. Whitman, Ben C. Askew, Le T. Duong, Carmen Fernandez-Metzler, Wasyl Halczenko, George D. Hartman, John H. Hutchinson, Chih-Tai Leu, Thomayant Prueksaritanont, Gideon A. Rodan, Sevgi B. Rodan,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 257 KB

english, 2004

9

Nonpeptide αvβ3 antagonists: identification of potent, chain-shortened 7-oxo RGD mimetics

Amy E. Zartman, Le T. Duong, Carmen Fernandez-Metzler, George D. Hartman, Chih-Tai Leu, Thomayant Prueksaritanont, Gideon A. Rodan, Sevgi B. Rodan, Mark E. Duggan, Robert S. Meissner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

10

Nonpeptide αvβ3 antagonists. Part 2: constrained glycyl amides derived from the RGD tripeptide

Robert S. Meissner, James J. Perkins, Le T. Duong, George D. Hartman, William F. Hoffman, Joel R. Huff, Nathan C. Ihle, Chih-Tai Leu, Rose M. Nagy, Adel Naylor-Olsen, Gideon A. Rodan, Sevgi B. Rodan,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

11

Non-Peptide αvβ3 antagonists. Part 3: Identification of potent RGD mimetics incorporating novel β-Amino acids as aspartic acid replacements

Paul J Coleman, Karen M Brashear, Cecilia A Hunt, William F Hoffman, John H Hutchinson, Michael J Breslin, Carol A McVean, Ben C Askew, George D Hartman, Sevgi B Rodan, Gideon A Rodan, Chih-Tai Leu, T

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 122 KB

english, 2002

12

Non-peptide αvβ3 antagonists. Part 5: identification of potent RGD mimetics incorporating 2-aryl β-amino acids as aspartic acid replacements

Karen M Brashear, Cecilia A Hunt, Brian T Kucer, Mark E Duggan, George D Hartman, Gideon A Rodan, Sevgi B Rodan, Chi-Tai Leu, Thomayant Prueksaritanont, Carmen Fernandez-Metzler, Andrea Barrish, Carl

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 120 KB

english, 2002

13

Involvement of αvβ3integrins in osteoclast function

Ichiro Nakamura, Le T. Duong, Sevgi B. Rodan, Gideon A. Rodan

Journal:

Journal of Bone and Mineral Metabolism

Year:

2007

Language:

english

File:

PDF, 520 KB

english, 2007

14

An activity-based probe for the determination of cysteine cathepsin protease activities in whole cells

Jean-Pierre Falgueyret, W. Cameron Black, Wanda Cromlish, Sylvie Desmarais, Sonia Lamontagne, Christophe Mellon, Denis Riendeau, Sevgi Rodan, Paul Tawa, Gregg Wesolowski, Kathryn E. Bass, Shankar Venk

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 583 KB

english, 2004

15

Non-peptide αvβ3 antagonists: Identification of potent, chain-shortened RGD mimetics that incorporate a central pyrrolidinone constraint

James J Perkins, L.T Duong, Carmen Fernandez-Metzler, George D Hartman, Donald B Kimmel, Chih-Tai Leu, Joseph J Lynch, Thomayant Prueksaritanont, Gideon A Rodan, Sevgi B Rodan, Mark E Duggan, Robert S

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

16

Non-peptide αvβ3 antagonists. Part 7: 3-Substituted tetrahydro-naphthyridine derivatives

Jiabing Wang, Michael J. Breslin, Paul J. Coleman, Mark E. Duggan, Cecilia A. Hunt, John H. Hutchinson, Chih-Tai Leu, Sevgi B. Rodan, Gideon A. Rodan, Le T. Duong, George D. Hartman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

17

Peptidic 1-cyanopyrrolidines: synthesis and SAR of a series of potent, selective cathepsin inhibitors

Robert M Rydzewski, Clifford Bryant, Renata Oballa, Gregg Wesolowski, Sevgi B Rodan, Kathryn E Bass, Darren H Wong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

18

Clonal differences in prostaglandin synthesis among osteosarcoma cell lines

Dr. Sevgi B. Rodan, Gregg Wesolowski, Gideon A. Rodan

Journal:

Journal of Bone and Mineral Research

Year:

1986

Language:

english

File:

PDF, 687 KB

english, 1986

19

Isolation and Characterization of Highly Enriched, Prefusion Mouse Osteoclastic Cells

Gregg Wesolowski, Le T. Duong, Päivi T. Lakkakorpi, Rose M. Nagy, Ken-Ichi Tezuka, Hirofumi Tanaka, Gideon A. Rodan, Sevgi B. Rodan

Journal:

Experimental Cell Research

Year:

1995

File:

PDF, 746 KB

1995

20

Cathepsin K - A Novel Molecular Target for Treatment of Osteoporosis: Discovery of Odanacatib

Journal:

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

21

ADENYLATE CYCLASE IN MUSCULAR DYSTROPHY

Gideon A. Rodan, Sevgi B. Rodan, Donald G. Raible, Leslie S. Cutler, Mary Wacholtz, Ramadan I. Sha'afi

Journal:

Annals of the New York Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 1.43 MB

english, 1979

22

Maintenance of parathyroid hormone response in clonal rat osteosarcoma lines

Robert J. Majeska, Sevgi B. Rodan, Gideon A. Rodan

Journal:

Experimental Cell Research

Year:

1978

Language:

english

File:

PDF, 365 KB

english, 1978

23

Bone resorptive factor produced by osteosarcoma cells with osteoblastic features is PGE2

Sevgi B. Rodan, Gideon A. Rodan, Hollis A. Simmons, Ronald W. Walenga, Maurice B. Feinstein, Lawrence G. Raisz

Journal:

Biochemical and Biophysical Research Communications

Year:

1981

Language:

english

File:

PDF, 1.00 MB

english, 1981

24

A Tumor-Secreted Protein Associated with Human Hypercalcemia of Malignancy : Biology and Molecular Biology

MICHAEL ROSENBLATT, MICHAEL P. CAULFIELD, JOHN E. FISHER, NOBORU HORIUCHI, ROBERTA L. MCKEE, SEVGI B. RODAN, MARK A. THIEDE, DAVID D. THOMPSON, J. GREGORY SEEDOR, RUTH E. NUTT, MARK E. GOLDMAN, JANE E

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 498 KB

english, 1988

25

Cathepsin K – A new molecular target for osteoporosis

Rodan, Sevgi B, Duong, Le T

Journal:

Year:

2008

Language:

english

File:

PDF, 1.75 MB

english, 2008

26

A Novel Class of Nonpeptidic Biaryl Inhibitors of Human Cathepsin K

Robichaud, Joël, Oballa, Renata, Prasit, Peppi, Falgueyret, Jean-Pierre, Percival, M. David, Wesolowski, Gregg, Rodan, Sevgi B., Kimmel, Donald, Johnson, Colena, Bryant, Cliff, Venkatraman, Shankar, S

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 521 KB

english, 2003

27

Binding Model for Nonpeptide Antagonists of α v β 3 Integrin

Feuston, Bradley P., Culberson, J. Chris, Duggan, Mark E., Hartman, George D., Leu, Chih-Tai, Rodan, Sevgi B.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 1.20 MB

english, 2002

28

Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L

Falgueyret, Jean-Pierre, Oballa, Renata M., Okamoto, Osamu, Wesolowski, Gregg, Aubin, Yves, Rydzewski, Robert M., Prasit, Peppi, Riendeau, Denis, Rodan, Sevgi B., Percival, M. David

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 197 KB

english, 2001

29

Parathyroid hormone and isoproterenol stimulation of adenylate cyclase in rat osteosarcoma clonal cells Hormone competition and site heterogeneity

Rodan, Sevgi B., Rodan, Gideon A.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1981

Language:

english

File:

PDF, 502 KB

english, 1981

30

The role of Mg2+ in hormone stimulation of rat osteosarcoma adenylate cyclase

Rodan, Sevgi B., Rodan, Gideon A.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1981

Language:

english

File:

PDF, 487 KB

english, 1981

31

Protein-Tyrosine Phosphatase Activity Regulates Osteoclast Formation and Function: Inhibition by Alendronate

Azriel Schmidt, Su Jane Rutledge, Naoto Endo, Evan E. Opas, Hirofumi Tanaka, Gregg Wesolowski, Chih Tai Leu, Zheng Huang, Chidambaram Ramachandaran, Sevgi B. Rodan and Gideon A. Rodan

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.08 MB

english, 1996

32

Nonpeptide α v β 3 Antagonists. 1. Transformation of a Potent, Integrin-Selective α IIb β 3 Antagonist into a Potent α v β 3 Antagonist

Duggan, Mark E., Duong, Le T., Fisher, John E., Hamill, Terence G., Hoffman, William F., Huff, Joel R., Ihle, Nathan C., Leu, Chih-Tai, Nagy, Rose M., Perkins, James J., Rodan, Sevgi B., Wesolowski, G

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

33

Effects of Acidic and Basic Fibroblast Growth Factors on Osteoblastic Cells

Rodan, Sevgi B., Wesolowski, Gregg, Thomas, Kenneth A., Yoon, Kyonggeun, Rodan, Gideon A.

Journal:

Connective Tissue Research

Year:

1989

Language:

english

File:

PDF, 255 KB

english, 1989

34

SV-40 Large-T Immortalization of Embryonic Bone Cells: Establishment of Osteoblastic Clonal Cell Lines

Heath, Joan K., Rodan, Sevgi B., Yoon, Kyonggeun, Rodan, Gideon A.

Journal:

Connective Tissue Research

Year:

1989

Language:

english

File:

PDF, 311 KB

english, 1989

35

The Role of Prostaglandins in Bone Formation

Harada, Shun-Ichi, Balena, Raffaella, Rodan, Gideon A., Rodan, Sevgi B.

Journal:

Connective Tissue Research

Year:

1995

Language:

english

File:

PDF, 440 KB

english, 1995

36

The Integrin Ligand Echistatin Prevents Bone Loss in Ovariectomized Mice and Rats

Yamamoto, Michiko, Fisher, John E., Gentile, Michael, Seedor, J. Gregory, Leu, Chih-Tai, Rodan, Sevgi B., Rodan, Gideon A.

Journal:

Year:

1998

Language:

english

File:

PDF, 546 KB

english, 1998

37

Parathyroid Hormone-Responsive Clonal Cell Lines from Rat Osteosarcoma*

MAJESKA, ROBERT J., RODAN, SEVGI B., RODAN, GIDEON A.

Journal:

Year:

1980

Language:

english

File:

PDF, 2.22 MB

english, 1980

38

Rat Calvarial Cell Lines Immortalized with SV-40 Large T Antigen: Constitutive and Retinoic Acid- Inducible Expression of Osteoblastic Features

ARSENIJEVIC, WAN, HEATH, JOAN K., RODAN, SEVGI B., YOON, KYONGGEUN, RODAN, GIDEON A.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.43 MB

english, 1989

39

Evidence for Preferential Effects of Parathyroid Hormone, Calcitonin and Adenosine on Bone and Periosteum 1

PECK, WILLIAM A., BURKS, JAMES K., WILKINS, JULIE, RODAN, SEVGI B., RODAN, GIDEON A.

Journal:

Year:

1977

Language:

english

File:

PDF, 757 KB

english, 1977

40

The Effect of Dexamethasone on Parathyroid Hormone Stimulation of Adenylate Cyclase in ROS 17/2.8 Cells*

RODAN, SEVGI B., FISCHER, MARILYN K., EGAN, JOHN J., EPSTEIN, PAUL M., RODAN, GIDEON A.

Journal:

Year:

1984

Language:

english

File:

PDF, 942 KB

english, 1984

41

Leukemia Inhibitory Factor Binds with High Affinity to Preosteoblastic RCT-1 Cells and Potentiates the Retinoic Acid Induction of Alkaline Phosphatase

RODAN, SEVGI B., WESOLOWSKI, GREGG, HILTON, DOUGLAS J., NICOLA, NICOS A., RODAN, GIDEON A.

Journal:

Year:

1990

Language:

english

File:

PDF, 986 KB

english, 1990

42

Effects of Retinoic Acid on Alkaline Phosphatase Messenger Ribonucleic Acid, Catecholamine Receptors, and G Proteins in ROS 17/2.8 Cells

IMAI, YASUO, RODAN, SEVGI B., RODAN, GIDEON A.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.15 MB

english, 1988

43

Comparison of bone and osteosarcoma adenylate cyclase. Effects of Mg 2+ , Ca 2+ , ATP 4− and HATP 3− in the assay mixture

Rodan, Sevgi B., Golub, Ellis E., Egan, John J., Rodan, Gideon A.

Journal:

Biochemical Journal

Year:

1980

Language:

english

File:

PDF, 1.22 MB

english, 1980

44

Dexamethasone Effects on β -Adrenergic Receptors and Adenylate Cyclase Regulatory Proteins G s and G i in ROS 17/2.8 Cells *

RODAN, SEVGI B., RODAN, GIDEON A.

Journal:

Year:

1986

Language:

english

File:

PDF, 1.49 MB

english, 1986

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